High-risk category:

• Patients with a prosthetic cardiac valve
• Patients with previous IE
• Congenital heart disease (CHD) – the following conditions only:
  • Unrepaired cyanotic CHD, including palliative shunts and conduits
  • Completely repaired congenital heart defect with prosthetic material or device, whether placed by surgery or by catheter intervention, during the first 6 months after the procedure (i.e. pre-endothelialisation)
  • Repaired CHD with residual defects at the site or adjacent to the site of a prosthetic patch or prosthetic device (which inhibit endothelialisation)
• Cardiac transplantation recipients who develop cardiac valvulopathy