Guidelines for Surgery Antibiotic Prophylaxis - Post-operative antibiotics

•  Studies have shown that giving additional antibiotic prophylaxis after wound closure does not reduce infection rates further.
• Giving further antibiotic doses has been shown to increase the risk of C.Difficile infection
• Post-operative antibiotics should only be given to treat active/on-going infection (e.g. perforated appendectomy) unless specifically recommended against the surgical procedure.

Caution; the antibiotic doses recommended on this website are intended for adult patients with normal renal and liver function unless otherwise stated. Dosing advice for patients with renal impairment is available here.

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