Renal dosing of Cefuroxime IV

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Cefuroxime IV: Dose adjustment for renal impairment

Cockcroft-Gault CrCl estimates (using the creatinine clearance calculator) should be used for drug dosing rather than the automated MDRD eGFR produced by the clinical chemistry laboratory available on NOTIS.

CrCl (ml/min)	Dose
20 – 50	Normal
10 – 20	750mg - 1.5g every 12 hours
<10	750mg every 12 hours.

Refer to renal pharmacist for advice on dosing in haemodialysis and peritoneal dialysis.

Refer to critical care pharmacist for advice on dosing in CVVH.

Page last edited: 28/04/2009

Caution; the antibiotic doses recommended on this website are intended for adult patients with normal renal and liver function unless otherwise stated. Dosing advice for patients with renal impairment is available here.