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Spontaneous Bacterial Peritonitis- Secondary prophylaxis:

Continuous Prophylaxis Regimen:

Co-trimoxazole PO 960mg OD (N.B. contains sulphonamide and trimethoprim)

Allergic to sulphonamides, trimethoprim or Co-trimoxazole(Septrin®) Discuss with medical microbiologist/gastroenterologist

The Full Guideline "Antibiotic Guidelines for Adult Patients with Spontaneous Bacterial Peritonitis or Liver Cirrhosis with Upper Gastrointestinal Bleed." is available here. 

Caution; the antibiotic doses recommended on this website are intended for adult patients with normal renal and liver function unless otherwise stated. Dosing advice for patients with renal impairment is available here.

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