Penicillin V (No SPC)

• A penicillin
• Absorption reduced by food therefore take on an empty stomach.
• Usual adult dose 500mg qds orally.
• Lower doses used prophylactically post-splenectomy.

Main indications:

• Prophylaxis following splenectomy.

Active against most strains of:

• Streptococci (Group A, B, C, G, viridans, pneumoniae, milleri)
• Neisseria meningitidis
• Neisseria gonorrhoea - although many strains have low level resistance
• Clostridium difficile
• Clostridium perfringens

Not active against most strains of:

• Staphylococci
• Coliforms
• Haemophilus
• Pseudomonas
• Bacteroides

Page last edited: 13/11/2008

Caution; the antibiotic doses recommended on this website are intended for adult patients with normal renal and liver function unless otherwise stated. Dosing advice for patients with renal impairment is available here.

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