Pseudomonas. 

• Gram-negative aerobic bacilli. 

• Common in any moist environment (including hospital sinks) and may colonise detergent or disinfectant solutions. 

• Frequently colonises chronic leg ulcers. 

• Typically resistant to many antibiotics and some strains are resistant to most available agents.

• Main pathogen is P. aeruginosa.

Main clinical manifestations:

• Catheter-associated UTI

• Pneumonia

• Septicaemia

• Exacerbations of bronchiectasis

• Malignant otitis media

• Serious infections are usually seen in debilitated or immunocompromised patients. 

Usually sensitive to:

• Ceftazidime

• Piperacillin/tazobactam  

• Aminoglycosides (gentamicin, tobramycin, amikacin)

• Carbapenems (imipenem, meropenem)

• Ciprofloxacin

• Colistin  

Usually resistant to:

• Most other antibiotics.

Page last edited: 16/01/2009

Caution; the antibiotic doses recommended on this website are intended for adult patients with normal renal and liver function unless otherwise stated. Dosing advice for patients with renal impairment is available here.

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